منابع مشابه
Type IV secretion and H.pylori transformation
Helicobacter pylori colonizes the gastric mucosa of humans and, if left untreated, this will result in a lifelong gastritis. Although infection is usually asymptomatic, it can manifest clinically as peptic or duodenal ulcers. Additionally, colonization with H.pylori is believed to induce gastric atrophy and increase the risk of gastric cancer. New genotypes of H. pylori are generated by recombi...
متن کاملMammary gland secretion: hormonal coordination of endocytosis and exocytosis.
The mammary epithelium coordinates the uptake of milk precursors and the transport of milk components in order to produce milk of relatively constant composition at a particular stage of lactation, as long as the mammary gland is healthy. The mammary epithelial cell controls the uptake of blood-borne molecules at its basal side and the release of products into milk at its apical side, through m...
متن کاملNamed Entity Recognition for Bacterial Type IV Secretion Systems
Research on specialized biological systems is often hampered by a lack of consistent terminology, especially across species. In bacterial Type IV secretion systems genes within one set of orthologs may have over a dozen different names. Classifying research publications based on biological processes, cellular components, molecular functions, and microorganism species should improve the precisio...
متن کاملF factor conjugation is a true type IV secretion system.
The F sex factor of Escherichia coli is a paradigm for bacterial conjugation and its transfer (tra) region represents a subset of the type IV secretion system (T4SS) family. The F tra region encodes eight of the 10 highly conserved (core) gene products of T4SS including TraAF (pilin), the TraBF, -KF (secretin-like), -VF (lipoprotein) and TraCF (NTPase), -EF, -LF and TraGF (N-terminal region) wh...
متن کاملCoupling factors in macromolecular type-IV secretion machineries.
Type IV secretion systems (T4SSs) are bacterial multiprotein organelles specialised in the transfer of (nucleo)protein complexes across cell membranes. They are essential for conjugation, bacterial-induced tumour formation in plant cells, as observed in Agrobacterium, toxin secretion, like in Bordetella and Helicobacter, cell-to-cell translocation of virulence factors, and intracellular activit...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1922
ISSN: 0306-3283
DOI: 10.1042/bj0160825